Inflammatory bowel disease is associated with an increased risk of cardiovascular events in a sex and age-dependent manner: A historical cohort study.

ABSTRACT:

Background

The relationship between inflammatory bowel diseases (IBD) and the risk of ischemic heart diseases (IHD) remains a subject of debate. In this study, we sought to investigate the association between IBD and long-term risk of IHD in a substantial cohort of IBD patients.

Methods

In this retrospective cohort study we utilized data from a state-mandated provider in Israel (Maccabi Healthcare Services). We identified all eligible patients diagnosed with IBD between 1/1990 and 7/2021 that were individually matched by sex-and-birth date to 10 MHS members with no indication of IBD. Study population was followed through the data until 12/2021 to examine the occurrence of IHD events.

Results

A total of 14,768 IBD patients (6144 UC, 8624 CD) and 120338 matched non-IBD

SUBMITTER: Cohen-Heyman N 

PROVIDER: S-EPMC11760278 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature