HER2 positive primary breast squamous cell carcinoma with good prognosis: a case report.

ABSTRACT:

Background

Primary breast squamous cell carcinoma (PBSCC) is a unique histopathological type of breast cancer. The majority of current case reports of PBSCC are triple-negative tumors with poor prognosis. Due to its heterogeneous clinical course, no unified management is achieved. Here, we report a human epidermal growth factor receptor 2 (HER2) positive case with good clinical outcome, which may contribute to the development of appropriate guidelines and imprecise management of PBSCC.

Case description

A 45-year-old female presented with a painless mass in the medial-upper quadrants of right breast and the imaging examination suggested a malignant tumor. She received modified radical mastectomy and axillary sentinel lymph node dissection of the right breast, and the patholog

SUBMITTER: Li Y 

PROVIDER: S-EPMC11760515 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature