Mohs micrographic surgery for the treatment of invasive melanoma: A systematic review with meta-analyses.

ABSTRACT:

Background

The use of Mohs micrographic surgery (MMS) in melanoma treatment has divided opinion and evidence-based guidelines are lacking.

Objectives

This systematic review aimed to analyse clinical outcomes for patients with invasive melanomas treated with Mohs rather than wide local excision (WLE).

Methods

Embase, MEDLINE and Cochrane databases (to 30 August 2023) were searched for studies using Mohs to treat invasive melanoma. Outcomes of interest were local recurrence and death from melanoma.

Results

Thirty-five articles involving 41,499 patients with invasive melanoma treated with Mohs were identified. Sixteen studies compared Mohs with WLE and 19 were Mohs-only, non-comparative studies. Patients treated with Mohs differed significantly from those undergoi

SUBMITTER: Williams GJ 

PROVIDER: S-EPMC11760679 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature