Prevalence of dengue and leptospirosis coinfection and associated mortality rates: a systematic review and meta-analysis.

ABSTRACT:

Background

Dengue and leptospirosis are prominent vector-borne diseases in tropical and subtropical regions, sharing overlapping geographic distribution and clinical presentations, which complicates diagnosis and management. Co-infection of these pathogens places additional strain on healthcare resources in endemic areas. This study aims to systematically estimate the prevalence and mortality rates of dengue and leptospirosis co-infections and assess their clinical implications.

Methods

Adhering the PRISMA 2020 guidelines and registered in the PROSPERO database, we conducted a systematic review and meta-analysis using the PubMed, Embase, and Web of Science databases up to October 2024. Nested Knowledge was used for screening and data extraction. Studies reporting quantitativ

SUBMITTER: Tiwari S 

PROVIDER: S-EPMC11760719 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature