Self-organized and self-sustained ensemble activity patterns in simulation of mouse primary motor cortex.

ABSTRACT: The idea of self-organized signal processing in the cerebral cortex has become a focus of research since Beggs and Plentz¹ reported avalanches in local field potential recordings from organotypic cultures and acute slices of rat somatosensory cortex. How the cortex intrinsically organizes signals remains unknown. A current hypothesis was proposed by the condensed matter physicists Bak, Tang, and Wiesenfeld² when they conjectured that if neuronal avalanche activity followed inverse power law distributions, then brain activity may be set around phase transitions within self-organized signals. We asked if we would observe self-organized signals in an isolated slice of our data driven detailed simulation of the mouse primary motor cortex? If we did, would we observe avala

SUBMITTER: Doherty DW 

PROVIDER: S-EPMC11760730 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature