International consensus on methotrexate dosing for patients with atopic dermatitis: An eDelphi study.

ABSTRACT:

Background

Despite the widespread off-label use of methotrexate (MTX) for the treatment of atopic dermatitis (AD), there is limited high-quality evidence on dosing regimens and existing guidelines do not provide clear recommendations regarding dosing strategies.

Objective

The aim of this study was to achieve international consensus among AD experts to standardize the dosing regimen for MTX treatment in adults and children with AD.

Methods

An electronic Delphi (eDelphi) study was conducted from October 2021 to September 2022. Recruitment was conducted through dermatology societies and AD interest groups. Participation was open to dermatologists and dermatology residents experienced in treating AD patients with MTX. The study consisted of three online rounds. The first

SUBMITTER: Caron AGM 

PROVIDER: S-EPMC11761001 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature