Autoimmune blistering diseases treated with glucocorticoids: An international study of steroid-induced myopathy.

ABSTRACT:

Background

Patients with autoimmune blistering diseases (AIBDs) are often exposed to chronic glucocorticoid (GC) treatment with many side effects. Glucocorticoid-induced myopathy (GIM) is a well-established side effect, which particularly affects the proximal muscles. The Glucocorticoid Toxicity Index (GTI) is a validated global assessment tool which quantifies GC toxicity over time.

Objectives

This study marks the first study which analyses GIM in patients with AIBDs. The objectives of this study were to utilize the GTI to investigate the nature and prevalence of GIM in AIBD patients and explore potential risk factors.

Methods

This international cohort study was conducted in blistering disease clinics across Australia, China, Greece, Iran, Japan, the Philippines, Tur

SUBMITTER: He A 

PROVIDER: S-EPMC11761005 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature