Comparative metabolic study of planktonic and sessile cells in Salmonella Enteritidis ATCC 13076: Elucidating metabolic pathways driving biofilm formation.

ABSTRACT: Microorganisms tend to accumulate on surfaces, forming aggregates such as biofilms, which grant them resistance to various environmental stressors and antimicrobial agents. This ability has hindered the effective treatment of diseases caused by pathogenic microorganisms, including Salmonella, which is responsible for a significant number of deaths worldwide. This study aimed to compare the metabolic profiles of planktonic and sessile cells of Salmonella Enteritidis using a metabolomics approach. The metabolites extracted from the bacterial cells were analyzed by LC/MS approach. Raw data were analyzed using Thermo Xcalibur v 3.1 software. For data processing, XCMS was used for feature detection, retention time, correction and alignment. The data matrix was analyzed by uni- and multivariate

SUBMITTER: Guillin Y 

PROVIDER: S-EPMC11761094 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature