The strategy to control the outbreak of an emerging respiratory infectious disease in a simulated Chinese megacity.

ABSTRACT:

Objectives

The emergence of respiratory infectious diseases (ERID) poses a significant threat to global public health. However, effectively managing ERID outbreaks in large cities remains a challenge.

Methods

An age-structured Susceptible-Exposed-Infectious-Removed (SEIR) model was developed to predict the effectiveness of non-pharmaceutical interventions (NPIs) in controlling ERID outbreaks. Four ERID outbreak scenarios were created based on varying levels of infectivity and pathogenicity. Based on the World Health Organization's (WHO) categorization for responding to the influenza pandemic, the combinations of NPIs were classified into five levels: base, any, moderate, high, and extraordinary levels (from mild to severe). The simulated progression of ERID outbreaks in a me

SUBMITTER: Lei Z 

PROVIDER: S-EPMC11761331 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature