Abbreviated Duke Activity Status Index for Risk Stratification in Heart Failure.

ABSTRACT: The Duke activity status index (DASI), a self-administered 12-item questionnaire has been used to estimate functional capacity and recently demonstrated prognostic information. We aimed to develop an abbreviated version for clinical applications. Leveraging the Cleveland Clinic GeneBank Study, we developed an abbreviated DASI questionnaire (aDASI) with the machine learning XGBoost algorithm, with the goal of maintaining the accuracy and reliability of the original DASI. We validated the prognostic value of aDASI in a subset of patients with heart failure from GeneBank and an independent data set from the GUIDE-IT (Guiding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure; ClinicalTrials.gov NCT01685840) trial. The results confirmed the congruence and accuracy be

SUBMITTER: Augusto SN 

PROVIDER: S-EPMC11761384 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature