Community-Based Cluster-Randomized Trial to Reduce Opioid Overdose Deaths.

ABSTRACT:

Background

Evidence-based practices for reducing opioid-related overdose deaths include overdose education and naloxone distribution, the use of medications for the treatment of opioid use disorder, and prescription opioid safety. Data are needed on the effectiveness of a community-engaged intervention to reduce opioid-related overdose deaths through enhanced uptake of these practices.

Methods

In this community-level, cluster-randomized trial, we randomly assigned 67 communities in Kentucky, Massachusetts, New York, and Ohio to receive the intervention (34 communities) or a wait-list control (33 communities), stratified according to state. The trial was conducted within the context of both the coronavirus disease 2019 (Covid-19) pandemic and a national surge in the number of

SUBMITTER: HEALing Communities Study Consortium 

PROVIDER: S-EPMC11761538 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature