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The prognostic value of systemic inflammation response index in digestive system carcinomas: a systematic review and meta-analysis.


ABSTRACT:

Background

Digestive system carcinomas (DSC) constitute a significant proportion of solid tumors, with incidence rates rising steadily each year. The systemic inflammation response index (SIRI) has been identified as a potential prognostic marker for survival in various types DSC. This meta-analysis aimed to evaluate the prognostic value of SIRI in patients with DSC.

Methods

We conducted a comprehensive literature search of PubMed, Web of Science Core Collection, Embase, and Cochrane Library databases, searching for studies published from inception to May 30, 2023. Eligible studies included cohort studies that assessed the association between pre-treatment SIRI levels and DSC prognosis. We extracted and synthesized hazard ratios (HRs) and 95% confidence intervals (CIs) using

SUBMITTER: Niu ZH 

PROVIDER: S-EPMC11761727 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature