Use of Stiripentol in Patients with Dravet Syndrome: Common Practice Among Experts in Spain.

ABSTRACT:

Background

Despite considerable evidence for the efficacy and safety of stiripentol in Dravet syndrome (DS), some aspects of stiripentol use remain challenging in clinical practice, such as dose titration and the adjustment of concomitant antiseizure medications (ASMs) to prevent potential adverse effects.

Aim

To (1) provide practical recommendations on the initiation of stiripentol treatment in patients with DS, (2) evaluate its effectiveness in the patient, and (3) guide the management of drug interactions and other aspects of treatment monitoring.

Methods

Six Spanish neurologists (the authors) with expertise in the management of pediatric and adult patients with DS held a meeting in early 2024 to develop expert recommendations regarding the use of stiripentol in DS

SUBMITTER: Garcia-Penas JJ 

PROVIDER: S-EPMC11762041 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature