Enlargement of the human prefrontal cortex and brain mentalizing network: anatomically homogenous cross-species brain transformation.

ABSTRACT: To achieve a better understanding of the evolution of the large brain in humans, a comparative analysis of species differences in the brains of extant primate species is crucial, as it allows direct comparisons of the brains. We developed a method to achieve anatomically precise region-to-region homologous brain transformations across species using computational neuroanatomy. Utilizing three-dimensional neuroimaging data from humans (Homo sapiens), chimpanzees (Pan troglodytes), and Japanese macaques (Macaca fuscata), along with the anatomical labels of their respective brains, we aimed to create a cross-species average template brain that preserves neuroanatomical correspondence across species. Homologous transformation of the brain from one species to another can be computed using the cr

SUBMITTER: Amano H 

PROVIDER: S-EPMC11762074 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature