Toxicodynamic insights of 2C and NBOMe drugs - Is there abuse potential?

ABSTRACT: Drug use represents a prevalent and multifaceted societal problem, with profound implications for public health, social welfare, and economic stability. To circumvent strict international drug control regulations, there is a growing trend in the development and market introduction of novel psychoactive substances (NPS), encompassing a wide range of compounds with psychoactive properties. This includes, among other classes of drugs, the phenethylamines. Originally derived from natural sources, these drugs have garnered particular attention due to their psychedelic effects. They comprise a broad spectrum of compounds, including 2,5-dimethoxyphenylethylamine (2C) drugs and their corresponding N-(2,5-dimethoxybenzyl)phenethylamine (NBOMe). Psychedelics are conventionally perceived as ha

SUBMITTER: Gil-Martins E 

PROVIDER: S-EPMC11762925 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature