Bioaugmented design and functional evaluation of low damage implantable array electrodes.

ABSTRACT: Implantable neural electrodes are key components of brain-computer interfaces (BCI), but the mismatch in mechanical and biological properties between electrode materials and brain tissue can lead to foreign body reactions and glial scarring, and subsequently compromise the long-term stability of electrical signal transmission. In this study, we proposed a new concept for the design and bioaugmentation of implantable electrodes (bio-array electrodes) featuring a heterogeneous gradient structure. Different composite polyaniline-gelatin-alginate based conductive hydrogel formulations were developed for electrode surface coating. In addition, the design, materials, and performance of the developed electrode was optimized through a combination of numerical simulations and physio-chemical charac

SUBMITTER: Wang L 

PROVIDER: S-EPMC11762938 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature