Delineation of reduced CTV2 on the basis of the characteristics and distribution of cervical lymph node metastasis in nasopharyngeal carcinoma.

ABSTRACT:

Introduction

The core objective of this study was to precisely locate metastatic lymph nodes, identify potential areas in nasopharyngeal carcinoma patients that may not require radiotherapy, and propose a hypothesis for reduced target volume radiotherapy on the basis of these findings. Ultimately, we reassessed the differences in dosimetry of organs at risk (OARs) between reduced target volume (reduced CTV2) radiotherapy and standard radiotherapy.

Methods and materials

A total of 209 patients participated in the study. We used image registration techniques to map patients' neck metastatic lymph nodes onto a template CT of healthy individuals. Using MIM software, we integrated all patients' lymph node images onto the template CT images and conducted an in-depth analysis of th

SUBMITTER: Wang Z 

PROVIDER: S-EPMC11763132 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature