Yeast cell wall polysaccharides accelerate yet in-feed antibiotic delays intestinal development and maturation via modulating gut microbiome in chickens.

ABSTRACT:

Background

It is important to promote intestinal development and maturation of chicks for feed digestion and utilization, intestinal health, and disease resistance. This study aimed to investigate the effects of dietary yeast cell wall polysaccharides (YCWP) addition on intestinal development and maturation of chickens and its potential action mechanism.

Methods

180 one-day-old male Arbor Acres broilers were randomly assigned to three groups containing control (basal diets without any antibiotics or anticoccidial drug), bacitracin methylene disalicylate (BMD)-treated group (50 mg/kg) and YCWP-supplemented group (100 mg/kg).

Results

Compared with control group, in-feed antibiotic BMD continuous administration significantly decreased crypt depth (d 21) and villus height

SUBMITTER: Guo F 

PROVIDER: S-EPMC11763161 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature