Is there a link between Hepatitis A virus and Guillain-Barre syndrome? A systematic review of case reports.

ABSTRACT:

Introduction

Guillain-Barré syndrome (GBS) is an inflammatory disorder of the peripheral nervous system, causing acute flaccid paralysis. There have been occasional reports linking Hepatitis A virus (HAV) to GBS. Here we aimed to evaluate the current literature on the association between GBS and HAV, exploring potential mechanisms and clinical implications.

Methods

We conducted a systematic search using PRISMA guidelines in PubMed, Web of Science, Embase, and Scopus. Only published case reports or conference abstracts presenting cases of confirmed HAV infection and GBS were included. Data extraction was performed independently by two reviewers, and quality assessment was conducted using the Joanna Briggs Institute critical appraisal tool.

Results

Out of 581 studies id

SUBMITTER: Ghasemi A 

PROVIDER: S-EPMC11763178 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature