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Sleep Behaviour in Sickle Cell Disease: A Systematic Review and Meta-Analysis.


ABSTRACT: Background/Objectives: There is a high prevalence of sleep behaviour disorders, as well as sleep disordered breathing (SDB), in individuals living with sickle cell disease (SCD). SDB has been systematically reviewed; therefore, this systematic review and meta-analysis focused on sleep behaviour. Methods: The comprehensive literature search, following PRISMA reporting guidelines, included all languages, conference proceedings and published theses from inception through February 2022. We identified 31 studies, with most of the research being conducted in North America, using polysomnography, actigraphy and questionnaires/diaries in paediatric SCD cohorts. Results: Total sleep time (TST) decreased, while sleep onset latency (SOL) increased with age. TST was higher on self

SUBMITTER: Koelbel M 

PROVIDER: S-EPMC11763464 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature