Prevalence and determinants of nasal carriage of penicillin non-susceptible <i>Streptococcus pneumoniae</i>: a cross-sectional household survey in northern Vietnam.

ABSTRACT:

Background

Beta-lactams remain the first-line treatment of Streptococcus pneumoniae infections despite the increasing global prevalence of penicillin-resistant/non-susceptible strains. We conducted a cross-sectional household survey in a rural community in northern Vietnam in 2018-2019 to provide prevalence estimates of penicillin non-susceptible S. pneumoniae (PNSP) carriage and to investigate behavioural and environmental factors associated with PNSP colonization. The data presented will inform the design of a large trial of population-based interventions targeting inappropriate antibiotic use.

Methods

A survey was conducted between July 2018 and April 2019, encompassing 1502 individuals from 324 households. A total of 1, 498 samples from nasal and nasopharyn

SUBMITTER: Tacoli C 

PROVIDER: S-EPMC11764309 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature