Gut microbial characteristics of the damp-heat constitution: a population-based multicenter cross-sectional study.

ABSTRACT:

Objective

To investigate the difference in gut microbiota between population with damp-heat constitution (DHC) and balanced constitution (BC).

Methods

A multi-centered cross-sectional case-control study was conducted, which included 249 participants with damp-heat constitution or balanced constitution. Baseline information of participants was collected, and stool samples were collected for gut microbiota analysis. Principal coordinate analysis, linear discriminant analysis effect size analysis, receiver operating characteristic, random forest model, and phylogenetic investigation of communities by reconstruction of unobserved states methods were used to reveal the relationship between gut microbiota and the damp-heat constitution.

Results

Compared to those in the BC g

SUBMITTER: Tianxing LI 

PROVIDER: S-EPMC11764936 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature