Restoration of Genuine Sensation and Proprioception of Individual Fingers Following Transradial Amputation with Targeted Sensory Reinnervation as a Mechanoneural Interface.

ABSTRACT: Background/Objectives: Tactile gnosis derives from the interplay between the hand's tactile input and the memory systems of the brain. It is the prerequisite for complex hand functions. Impaired sensation leads to profound disability. Various invasive and non-invasive sensory substitution strategies for providing feedback from prostheses have been unsuccessful when translated to clinical practice, since they fail to match the feeling to genuine sensation of the somatosensory cortex. Methods: Herein, we describe a novel surgical technique for upper-limb-targeted sensory reinnervation (ulTSR) and report how single digital nerves selectively reinnervate the forearm skin and restore the spatial sensory capacity of single digits of the amputated hand in a case series of seven pati

SUBMITTER: Gardetto A 

PROVIDER: S-EPMC11765609 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature