Molecular and Proteomic Analyses of Effects of Cadmium Exposure on the Silk Glands of <i>Trichonephila clavata</i>.

ABSTRACT: Cadmium (Cd) is a pervasive heavy metal pollutant released into the environment through industrial activities such as mining, smelting, and agricultural runoff. This study aimed to investigate the molecular and metabolic impacts of Cd exposure on the silk glands of Trichonephila clavata, a species renowned for producing silk with exceptional mechanical properties. Cd accumulation in spider bodies and silk glands was significantly higher in the low- and high-Cd groups compared to controls, with a dose- and time-dependent increase. Oxidative stress markers, including superoxide dismutase, glutathione peroxidase, peroxidase, and malondialdehyde, were significantly elevated, indicating a robust stress response. Proteomic analysis identified 2498 proteins, with 227 differentially express

SUBMITTER: Song Z 

PROVIDER: S-EPMC11765807 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature