Efficacy of Larval Therapy for Wounds: A Systematic Review and Meta-Analysis.

ABSTRACT: Background/Objective: Larval therapy (LT), an intervention using live fly larvae to remove necrotic tissue and promote healing, has regained attention in order to address the growing need for chronic wound management. LT was approved by the Food and Drug Administration (FDA) in 2004 to treat difficult-to-heal wounds; however, LT remains an underutilized therapy. To evaluate efficacy of LT in a systematic review and meta-analysis of wound outcomes from randomized controlled trials (RCTs). Methods: We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines to conduct a literature search across five databases for published and unpublished RCTs comparing LT to conventional therapy. A meta-analysis was performed to evaluate LT's effect o

SUBMITTER: Lam T 

PROVIDER: S-EPMC11765813 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature