Reference Values of Skin Autofluorescence by Age Groups in Healthy Spanish Adults: Results from the EVasCu Study, a Systematic Review, and a Meta-Analysis.

ABSTRACT: Background/Objectives: Age is a known predictor of skin autofluorescence (SAF) across populations, but age-based reference values are lacking for the Spanish population. This study aims to establish SAF reference values for healthy Spanish adults by age group, compare these with other populations, and estimate optimal SAF cut-off points by age range. Additionally, it aims to analyse the influence of sex, smoking, and skin phototype. Methods: This cross-sectional EVasCu study included 390 healthy subjects aged over 18 years. Participants' age, sex, smoking status, and skin were recorded and categorised into age groups. Advanced glycation end products were measured through the SAF. A systematic review and meta-analysis, including an EVasCu study, was performed to obtain pooled

SUBMITTER: Martinez-Garcia I 

PROVIDER: S-EPMC11766177 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature