The Origin(s) of LUCA: Computer Simulation of a New Theory.

ABSTRACT: Carl Woese's thesis of cellular evolution emphasized that the last universal common/cellular ancestor (LUCA) must have evolved by drawing from "global inventions". Yet, existing theories regarding the origin(s) of LUCA have mostly centered upon scenarios that LUCA had evolved mostly independently. In an earlier paper, we advanced a new theory regarding the origin(s) of LUCA that extends Woese's original insights. Our theory centers upon the possibility that different vesicles and protocells can merge with and acquire each other as a form of variation, selection, and retention, driven by wet-and-dry cycles and other similar cyclical processes. In this paper, we use computer simulation to show that under a variety of simulated conditions, LUCA can indeed be produced by our proposed processes

SUBMITTER: Tang S 

PROVIDER: S-EPMC11766493 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature