Chemical Changes Under Heat Stress and Identification of Dendrillolactone, a New Diterpene Derivative with a Rare Rearranged Spongiane Skeleton from the Antarctic Marine Sponge <i>Dendrilla antarctica</i>.

ABSTRACT: The waters around the western Antarctic Peninsula are experiencing fast warming due to global change, being among the most affected regions on the planet. This polar area is home to a large and rich community of benthic marine invertebrates, such as sponges, tunicates, corals, and many other animals. Among the sponges, the bright yellow Dendrilla antarctica is commonly known for using secondary diterpenoids as a defensive mechanism against local potential predators. From the dichloromethane extract of sponge samples from Deception Island collected in January 2023, we isolated a novel derivative with an unusual β-lactone diterpene skeleton here named dendrillolactone (1), along with seven previously described diterpenes, including deceptionin (2), a gracilane norditerpe

SUBMITTER: Profumo A 

PROVIDER: S-EPMC11767012 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature