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Comparison of Secondary Metabolite Extraction Methods in <i>Hamelia patens</i> Jacq. and Their Inhibitory Effect on <i>Fusarium oxysporum</i> f. sp. <i>radicis-lycopersici</i>.


ABSTRACT: Background: Hamelia patens Jacq. (HP) is widely recognized in traditional medicine for its antimicrobial properties, which are attributed to secondary metabolites such as phenolic compounds, alkaloids, and terpenes. Fusarium oxysporum f. sp. radicis-lycopersici (Fo), a phytopathogenic fungus affecting economically important crops, is managed with fungicides like benzimidazoles and azoles. Excessive use of these compounds has led to resistance and environmental contamination, highlighting the need for sustainable alternatives. This study aimed to optimize the extraction of secondary metabolites from HP leaves and flowers, evaluate their antifungal activity, and assess the impact of extraction methods and plant parts on chemical composition and efficacy. Method

SUBMITTER: Valle Ortiz DJ 

PROVIDER: S-EPMC11767014 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature