Advances and Mechanisms of RNA-Ligand Interaction Predictions.

ABSTRACT: The diversity and complexity of RNA include sequence, secondary structure, and tertiary structure characteristics. These elements are crucial for RNA's specific recognition of other molecules. With advancements in biotechnology, RNA-ligand structures allow researchers to utilize experimental data to uncover the mechanisms of complex interactions. However, determining the structures of these complexes experimentally can be technically challenging and often results in low-resolution data. Many machine learning computational approaches have recently emerged to learn multiscale-level RNA features to predict the interactions. Predicting interactions remains an unexplored area. Therefore, studying RNA-ligand interactions is essential for understanding biological processes. In this review, we ana

SUBMITTER: Zhuo C 

PROVIDER: S-EPMC11767038 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature