Transcriptome Analysis Revealed the Molecular Mechanism of Acetic Acid Increasing Monascus Pigment Production in Monascus ruber CICC41233.

ABSTRACT: The addition of acetic acid to Monascus ruber cultures is usually used to inhibit the growth of heterotrophic bacteria; however, we found that acetic acid also promotes the growth of M. ruber CICC41233, as well as the synthesis of Monascus pigments (MPs). Compared with no acetic acid or HCl addition, the diameter of M. ruber CICC41233 colonies increased significantly under acetic acid conditions. On the sixth day of fermentation, the yield of total pigments in M. ruber increased significantly by 9.97 times (compared with no acetic acid) and 13.9 times (compared with hydrochloric acid). The transcriptomics data showed that the differentially expressed genes between M. ruber with acetic acid and without acetic acid were mainly involved in starch and

SUBMITTER: Wang Y 

PROVIDER: S-EPMC11767103 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature