Phytochemical Composition and Antioxidant Activity of Manuka Honey and Ohia Lehua Honey.

ABSTRACT: Honey is abundant in bioactive compounds, which demonstrate considerable therapeutic effects, particularly on oxidative stress and inflammation.

Objectives

This work sought to evaluate the antioxidant mechanisms of Manuka honey (MH) and Ohia Lehua honey (OLH), correlating them with phytochemical analyses in a rat model of experimentally induced inflammation.

Methods

The identification of polyphenolic compounds in the extracts was carried out using HPLC-ESI MS. The extracts' antioxidant activity was evaluated in vitro through DPPH, FRAP, H₂O₂, and NO scavenging assays, while in vivo assessments included measurements of total oxidative status (TOS), total antioxidant capacity (TAC), oxidative stress index (OSI), advanced oxidation protein products (AOPP),

SUBMITTER: Morar II 

PROVIDER: S-EPMC11767333 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature