Human Milk Archaea Associated with Neonatal Gut Colonization and Its Co-Occurrence with Bacteria.

ABSTRACT: Archaea have been identified as early colonizers of the human intestine, appearing from the first days of life. It is hypothesized that the origin of many of these archaea is through vertical transmission during breastfeeding. In this study, we aimed to characterize the archaeal composition in samples of mother-neonate pairs to observe the potential vertical transmission. We performed a cross-sectional study characterizing the archaeal diversity of 40 human colostrum-neonatal stool samples by next-generation sequencing of V5-V6 16S rDNA libraries. Intra- and inter-sample analyses were carried out to describe the Archaeal diversity in each sample type. Human colostrum and neonatal stools presented similar core microbiota, mainly composed of the methanogens Methanoculleus and Metha

SUBMITTER: Salas-Lopez M 

PROVIDER: S-EPMC11767358 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature