Ellagic Acid from <i>Geranium thunbergii</i> and Antimalarial Activity of Korean Medicinal Plants.

ABSTRACT: This study investigates the antimalarial potential of extracts and compounds from various plants used in traditional Korean medicine, in response to the increasing resistance of Plasmodium falciparum to standard treatments such as chloroquine and artemisinin. The antimalarial activity screening was conducted on 151 extracts, identifying the top seven candidates, including Geranium thunbergii (50% ethanol and 100% methanol extract), Reynoutria japonica, Amomum villosum (hot water and 50% ethanol extract), Cinnamomum zeylanicum, and Platycodon grandiflorum. Among these, G. thunbergii was identified as the top priority for further analysis due to its high antimalarial activity and high yield of bioactive compounds. The plant extracts were fract

SUBMITTER: Jun H 

PROVIDER: S-EPMC11767465 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature