Vitamins K2 and D3 Improve Long COVID, Fungal Translocation, and Inflammation: Randomized Controlled Trial.

ABSTRACT:

Background

Long COVID (LC) is characterized by persistent symptoms at least 3 months after a SARS-COV-2 infection. LC has been associated with fungal translocation, gut dysfunction, and enhanced systemic inflammation. Currently, there is no approved treatment for this condition. The anti-inflammatory effect of vitamins K2 and D3 was shown to help attenuate the course of acute COVID-19 infection.

Objective and hypothesis

This trial aims to investigate the effects of vitamins K2/D3 on LC symptoms, as well as gut and inflammatory markers, in people with established long COVID. Our hypothesis is that by attenuating systemic inflammation, vitamins K2/D3 will improve long COVID symptoms.

Methods

This single-site randomized controlled study enrolled adults experiencing ≥2 mo

SUBMITTER: Atieh O 

PROVIDER: S-EPMC11767688 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature