Colorimetric Detection of Dopamine Based on Peroxidase-like Activity of β-CD Functionalized AuNPs.

ABSTRACT: Catalytically active nanomaterials, or nanozymes, have gained significant attention as alternatives to natural enzymes due to their low cost, ease of preparation, and enhanced stability. Because of easy preparation, excellent biocompatibility, and unique optoelectronic properties, gold nanoparticles (AuNPs) have attracted increasing attention in many fields, including nanozymes. In this work, we demonstrated the applicability of beta-cyclodextrin functionalized gold nanoparticles (β-CD-AuNPs) as enzyme mimics for different substances, including TMB and DA. We found that β-CD-AuNPs can catalyze the H₂O₂-mediated oxidation of DA. The dopamine signal-off sensor was developed by taking advantage of the peroxidase-like activity of β-CD-AuNPs towards TMB and DA, where both

SUBMITTER: Anderson S 

PROVIDER: S-EPMC11767741 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature