Vaginal Dysbiosis in Infertility: A Comparative Analysis Between Women with Primary and Secondary Infertility.

ABSTRACT: Infertility, both primary and secondary, is strongly influenced by microbiological factors, with the vaginal microbiota playing a key role in reproductive health.

Objective

The aim of this study was to characterize the vaginal microbiota of 136 Mexican women diagnosed with infertility-primary (n = 58) and secondary (n = 78)-by evaluating the presence of pathogenic bacterial species and their associations with infertility conditions.

Methods

Samples were obtained through cervical swabs, and microorganism identification was performed using qPCR techniques.

Results

Analysis revealed a positive correlation between increased age and the likelihood of primary infertility, as well as a negative correlation with secondary infertility. Significant differences in microbial compo

SUBMITTER: Cortes-Ortiz IA 

PROVIDER: S-EPMC11767898 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature