Pradofloxacin Minimum Inhibitory Concentration Profiling of <i>Streptococcus suis</i> Isolates: Insights into Antimicrobial Susceptibility in Swine.

ABSTRACT: This study evaluated the minimum inhibitory concentration (MIC) of pradofloxacin against various swine respiratory pathogens, including Bordetella bronchiseptica, Glaesserella parasuis, Mycoplasma hyopneumoniae, Pasteurella multocida, and Streptococcus suis (S. suis), associated with disease in swine. This research was conducted in two phases: the initial phase examined isolates from the lungs that could be either commensal or pathogenic, while the second phase focused on systemic S. suis strains that spread from the respiratory tract to the brain. The pradofloxacin MIC values of the second phase were within the MIC range of the initial phase, with MIC₅₀ and MIC₉₀ values highlighting its potential as an effective antimi

SUBMITTER: Risser J 

PROVIDER: S-EPMC11768269 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature