Multifunctional Biological Performance of Electrospun PCL Scaffolds Formulated with Silver Sulfide Nanoparticles.

ABSTRACT: Our work describes the green synthesis of silver sulfide nanoparticles (Ag₂S NPs) and their formulation into polycaprolactone fibers (PCL), aiming to improve the multifunctional biological performance of PCL membranes as scaffolds. For this purpose, an extract of rosemary (Salvia rosmarinus) was employed as a reducing agent for the Ag₂S NPs, obtaining irregular NPs and clusters of 5-60 nm, with a characteristic SPR absorption at 369 nm. Ag₂S was successfully incorporated into PCL fibers by electrospinning using heparin (HEP) as a stabilizer/biocompatibility agent, obtaining nanostructured fibers with a ca. 500-800 nm diameter. Different amounts of Ag₂S NPs (0.05, 0.5, and 1 wt.%) enhanced the nanostructured membranes' surface polarity and

SUBMITTER: Torres-Pedroza MDC 

PROVIDER: S-EPMC11768394 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature