Ethanolic Extract of <i>Averrhoa carambola</i> Leaf Has an Anticancer Activity on Triple-Negative Breast Cancer Cells: An In Vitro Study.

ABSTRACT: Background/Objectives: Averrhoa carambola, or star fruit, is a shrub known for its medicinal properties, especially due to bioactive metabolites identified in its roots and fruit with anti-cancer activity. However, the biological effects of its leaves remain unexplored. This study aimed to assess the effects of ethanolic extract from A. carambola leaves on triple-negative breast cancer (TNBC), an aggressive subtype lacking specific therapy. Methods: Phytochemical analysis and HPLC profile and additional cell line evaluation employing MDA-MB-231 were carried out. Results: Phytochemical screening revealed that the ethanolic extract was rich in flavonoids, saponins, and steroids, demonstrating an antioxidant capacity of 45%. ¹H NMR analysis indica

SUBMITTER: Beas-Guzman OF 

PROVIDER: S-EPMC11768879 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature