Post-Vaccination Anaphylaxis in Adults: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background/objectives

Vaccines have been recognized as one of the most effective public health interventions. However, vaccine-associated anaphylaxis, although rare, is a serious adverse reaction. The incidence of anaphylaxis related to non-COVID-19 vaccines in adults remains underreported. This systematic review and meta-analysis aim to estimate the incidence of post-vaccination anaphylaxis across various vaccines in adults.

Methods

A comprehensive literature search of PubMed, Embase, Scopus, and Web of Science identified studies on anaphylaxis following vaccination in adults (≥18 years), excluding COVID-19 vaccines. PRISMA 2020 guidelines were followed. The protocol was registered in PROSPERO in advance (ID CRD42024566928). Random-effects and fixed-effects models were used

SUBMITTER: Pennisi F 

PROVIDER: S-EPMC11769139 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature