Associations Between Ambient PM_2.5 and Thyroid Hormones in Pregnant Persons in Puerto Rico.

ABSTRACT:

Introduction

This study investigates associations between fine particulate air pollution (PM_2.5) exposure and thyroid hormone levels during pregnancy in Puerto Rican individuals, a vulnerable population facing socioeconomic and environmental disparities.

Methods

This research draws on data from the PROTECT cohort study and involves 1040 participants to measure the effect of PM_2.5 on developmentally important thyroid hormones (TSH, T3, T4, and FT4). Pollution concentrations were linked to participant locations using EPA air quality data and analyzed across two visits during gestational weeks 16-20 and 24-28.

Results

The results suggest that PM_2.5 exposure is positively associated with maternal T3, T4, and FT4 levels but not TSH. These e

SUBMITTER: Honda T 

PROVIDER: S-EPMC11769198 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature