Surveillance of Adverse Events Following Varicella Vaccine Immunization in Zhejiang Province, China, from 2020 to 2022.

ABSTRACT: Background: China has a high incidence rate of varicella yet a low coverage rate of the varicella vaccine (VarV), with safety concerns being a leading cause of the lack of vaccination willingness. This study aimed to describe VarV-related adverse events following immunization (AEFIs) and analyze their characteristics in Zhejiang, China, 2020-2022. Methods: VarV-related AEFIs in Zhejiang Province from 1 January 2020 to 31 December 2022 were collected through the Chinese National AEFI Information System (CNAEFIS) for a descriptive epidemiological analysis. Results: From 2020 to 2022, a total of 1477 VarV-related AEFI cases were reported (incidence rate: 34.79/100,000). The three most frequently reported clinical symptoms of common adverse reactions were fever, redness, a

SUBMITTER: Liang H 

PROVIDER: S-EPMC11769265 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature