New Evidence for <i>Cotinus coggygria</i> Scop. Extracts Application in Gastrointestinal Ailments.

ABSTRACT:

Background/objectives

Cotinus coggygria Scop. is traditionally used for treatment of various gastrointestinal ailments. In this study, we investigated the phytochemical profile and biological activities of leaves, bark and flowers extracts of C. coggygria. Methods: Phytochemical analysis was performed using HPLC. The antimicrobial activity of water and methanolic extracts of C. coggygria leaves, bark and flowers towards various oral fungal and bacterial strains of clinical origin was tested by use of a microdilution assay. Additionally, their cytotoxic activity was determined against different gastrointestinal carcinoma cell lines (CAL27, FaDu, SW480, HCT116 and MRC-5) in concentrations ranging from 3.125 to 400 µg/mL for 48 and 72 h.

Results

The presenc

SUBMITTER: Stojkovic D 

PROVIDER: S-EPMC11769289 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature