Integrated Serosurveillance of Infectious Diseases Using Multiplex Bead Assays: A Systematic Review.

ABSTRACT: Integrated serological surveillance (serosurveillance) involves testing for antibodies to multiple pathogens (or species) simultaneously and can be achieved using multiplex bead assays (MBAs). This systematic review aims to describe pathogens studied using MBAs, the operational implementation of MBAs, and how the data generated were synthesised. In November and December 2023, four databases were searched for studies utilising MBAs for the integrated serosurveillance of infectious diseases. Two reviewers independently screened and extracted data regarding the study settings and population, methodology, seroprevalence results, and operational implementation elements. Overall, 4765 studies were identified; 47 were eligible for inclusion, of which 41% (n = 19) investigated multiple mala

SUBMITTER: Ward S 

PROVIDER: S-EPMC11769346 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature