Gender-specific risks for incident cancer in patients with different heart failure phenotypes.

ABSTRACT:

Background

There is conflicting evidence regarding whether heart failure (HF) increases the risk of developing cancer.

Objective

This study aimed to assess the association between HF and incident cancer, considering gender differences and HF phenotypes.

Methods

This retrospective study was conducted on data of adult individuals, free of cancer at baseline, from the First Affiliated Hospital of Wenzhou Medical University between January 2009 and February 2023. The patients with HF were categorized as HF with preserved ejection fraction (HFpEF) and HF with reduced ejection fraction (HFrEF). The primary outcome was incident cancer, including obesity-related, tobacco-related, lung, colorectal and breast cancers.

Results

Of 33 033 individuals enrolled, 16 722 were d

SUBMITTER: Chen QF 

PROVIDER: S-EPMC11769628 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature