Advanced lung cancer inflammation index is associated with mortality in critically ill patients with heart failure.

ABSTRACT:

Aims

Nutrition and inflammation status play a vital role in the prognosis of patients with heart failure (HF). This study aimed to investigate the association between the advanced lung cancer inflammation index (ALI), a novel composite indicator of inflammation and nutrition, and short-term mortality among critically ill patients with HF.

Methods

This retrospective study included 548 critically ill patients with HF from the MIMIC-IV database. ALI was computed using body mass index, serum albumin and neutrophil-lymphocyte ratio. The primary endpoint was all-cause in-hospital mortality, and the secondary endpoint was 90 day mortality. Kaplan-Meier survival curve analysis with long-rank test and Cox proportional hazards regression models were employed to assess the relationship

SUBMITTER: Sun X 

PROVIDER: S-EPMC11769650 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature