Prognostic value of hypoxaemic burden from overnight oximetry in heart failure with preserved ejection fraction.

ABSTRACT:

Aims

Nocturnal hypoxaemic burden, quantified as time spent with oxygen saturation below 90% (T90), is an established independent predictor of mortality in heart failure (HF) with reduced ejection fraction. The prognostic value of T90 in HF with preserved ejection fraction (HFpEF) is unknown. This study aims to determine the association of T90 with adverse outcomes in HFpEF.

Methods and results

One hundred twenty-six patients prospectively included from our specialised HFpEF outpatient clinic underwent ambulatory home sleep monitoring to obtain oximetry data, including T90. We investigated the association between T90 and a composite endpoint of HF hospitalisations or all-cause mortality. Nocturnal hypoxaemic burden in this HFpEF population was high, with a median T90 of 13.7 

SUBMITTER: Mourmans SGJ 

PROVIDER: S-EPMC11769663 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature