Exercise training in left ventricular assist device patients: Protocol of an individual participant data meta-analysis.

ABSTRACT:

Aims

Although left ventricular assist device (LVAD) implantation improves prognosis of advanced heart failure patients still suffer from impaired exercise capacity and quality of life (QoL). Exercise training may improve both; however, the available evidence about exercise training effects in LVAD patients remains inconclusive due to small and monocentric randomized controlled trials. This study aims to aggregate the individual participant data (IPD) to perform meta-analysis on the safety and efficacy of exercise training on exercise capacity and QoL over standard care in LVAD patients.

Methods

Randomized controlled trials comparing exercise training and standard care (no supervised training) will be identified through database searching. Corresponding authors of eligible ra

SUBMITTER: Kambic T 

PROVIDER: S-EPMC11769664 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature