Childhood maltreatment and the structural development of hippocampus across childhood and adolescence.

ABSTRACT:

Background

Prior studies suggest that childhood maltreatment is associated with altered hippocampal volume. However, longitudinal studies are currently scarce, making it difficult to determine how alterations in hippocampal volume evolve over time. The current study examined the relationship between childhood maltreatment and hippocampal volumetric development across childhood and adolescence in a community sample.

Methods

In this longitudinal study, a community sample of 795 participants underwent brain magnetic resonance imaging (MRI) in three waves spanning ages 6-21 years. Childhood maltreatment was assessed using parent-report and children´s self-report at baseline (6-12 years old). Mixed models were used to examine the relationship between childhood maltreatment and hi

SUBMITTER: Doretto VF 

PROVIDER: S-EPMC11769901 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature